Description
The Double Marker Profile is a prenatal screening test typically performed during the first trimester of pregnancy. It measures two specific markers in maternal blood: free beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein A (PAPP-A). These markers, combined with maternal age and ultrasound findings, help assess the risk of chromosomal abnormalities such as Down syndrome (trisomy 21) and Edwards syndrome (trisomy 18) in the fetus. While not diagnostic, this test helps identify pregnancies that may benefit from further diagnostic testing.
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